• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Polyvalent immunotherapeutics of high specificity based on modified antibodies and lyophilized injectable formulation highly safe and effective. The invention relates to the production and development of a lyophilized injectable formulation of modified antibodies or variants thereof, highly specific neutralizing heterologous mixtures of proteins, peptides and other organic and inorganic components that have different specific activities and may include but are not limited to to venoms of poisonous animals. For convenience we will refer to poisons, but all kinds of poisons of terrestrial and marine animals are included. It is also directed to the production method that includes the hyperimmunization of mammals for the production of highly specific antibodies, the process of modification (fragmentation) and purification, and finally the injectable formulation lyophilized, which confers properties of high purity and high specificity. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2549690A2
    申请号:ES201300887
    申请日:2013-09-27
    公开日:2015-10-30
    发明作者:Juan LÓPEZ DE SILANES PÉREZ
    申请人:INOSAN BIOPHARMA S A；Inosan Biopharma Sa；
    IPC主号:
    专利说明:

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    权利要求:
    Claims (1)
    [1]
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    类似技术:
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    同族专利:
    公开号 | 公开日
    US20160368969A1|2016-12-22|
    FR2997084A1|2014-04-25|
    ES2549690B1|2016-09-21|
    ES2549690B8|2018-06-21|
    MX2012012132A|2013-12-08|
    ES2549690R1|2016-01-11|
    US20200190166A1|2020-06-18|
    MX367136B|2019-08-06|
    US10538577B2|2020-01-21|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    WO2019070108A1|2017-10-02|2019-04-11|Laboratorios Silanes S.A. De C.V.|High-performance process for producing poison-antidotes using f2 antibody fragments|US2065196A|1934-10-09|1936-12-22|Parfentjev Ivan Alexandrovich|Method for purification of antitoxins and the like|
    US2123198A|1936-10-23|1938-07-12|Lederle Lab Inc|Treatment of antitoxins and the like|
    US2175090A|1938-06-22|1939-10-03|Lederie Lab Inc|Purification of antibody compositions|
    US4849352A|1984-10-09|1989-07-18|Sullivan John B|Antibody purification process|
    EP0916678A3|1993-06-03|1999-05-26|Therapeutic Antibodies Inc.|Method of clotting blood|
    IN188098B|2000-03-09|2002-08-17|Serum Inst India Ltd|
    US6709655B2|2001-02-28|2004-03-23|Instituto Bioclon, S.A. De C.V.|Pharmaceutical composition of F2 antibody fragments and a process for the preparation thereof|
    WO2004007695A2|2002-03-08|2004-01-22|Osel, Inc.|Lactobacilli expressing biologically active polypeptides and uses thereof|
    WO2005009464A1|2003-07-25|2005-02-03|Lopez De Silanes Juan|Administration of anti-cytokine f2 antibody fragments|
    MXPA04008435A|2004-08-31|2006-03-02|Univ Mexico Nacional Autonoma|Immunogen and antivenom against violin spider venom.|
    MXPA06003717A|2006-04-03|2006-09-29|Silanes Sa De Cv Lab|Ophtalmic compositions proteins for inhibiting cytokins involved in immunologic inflamatory processes.|
    CN101816789B|2010-04-08|2012-09-05|成都军区疾病预防控制中心军事医学研究所|Lyophilized viper antivenin and preparation method thereof|
    法律状态:
    2016-09-21| FG2A| Definitive protection|Ref document number: 2549690 Country of ref document: ES Kind code of ref document: B1 Effective date: 20160921 |
    优先权:
    申请号 | 申请日 | 专利标题
    MX/A/2012/012132|2012-10-18|
    MX2012012132A|MX367136B|2012-10-18|2012-10-18|Novel highly-specified polyvalent immunotherapeutic drugs based on modified antibodies and highly-secure and effective injectable lyophilized formulation.|
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